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These parasites come from the sea and infect humans. The effect of this infection, lost of reasoning. The parasites make the people they infect lose control and become subject to impulses. Seine Miyazaki is the enemy of these Mushi, as she destroys them. 

If they are extracted too early, a deep wound will be left in the infected persons heart and leave them with the lingering urge to kill Seine instead of being completely healed.

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